A Study on different histological variants of Phyllodes tumour of Breast and Fibroadenoma with special emphasis to differentiate Fibroadenoma from Benign Phyllodes tumour – A Retrospective 2 years study in a Tertiary care centre

Dr Tripti Das
2018 Journal of Medical Science And clinical Research  
Fibroadenoma is the most common benign breast tumour in adolescent and young women of child bearing age group arising from the Terminal Duct Lobular Unit (TDLU) and featuring a proliferation of both epithelial and stromal elements. Phyllodes tumours are rare fibro epithelial tumours of the breast tumours account for0.3-1% of all primary tumours of the breast predominantly in middleaged women. Intracanalicular fibroadenoma with increased stromal cellularity closely mimics benign phyllodes tumour
more » ... but it has to be differentiated properly as clinical management and prognosis are different in both the cases. . Fibroadenomas were most common in the 11-20 yrs (45.67%) age group, followed by 21-30 yrs (36.22%), while phyllodes were more common in 41-50 yrs (36.84%) age group. Fibrocystic changes were present in 13.39% cases of fibroadenoma. Fibroadenoma and Benign Phyllodes tumour of breast were differentiated on the basis of 3 histological feature i.e. stromal cellularity, cellular pleomorphism and mitotic activity. Conclusion: There is various histomorphological variants of fibroadenoma and 3 types of phyllodes tumour; which were studied and this knowledge is very helpful where there is overlapping features of both the tumours and chance of confusion is present. Special emphasis was given to differentiate fibroadenoma from benign phyllodes.
doi:10.18535/jmscr/v6i6.122 fatcat:3haugl4eo5dxbdgxsj776r5vs4