Broken sleep predicts hardened blood vessels

Raphael Vallat, Vyoma D. Shah, Susan Redline, Peter Attia, Matthew P. Walker, Paul Shaw
2020 PLoS Biology  
Why does poor-quality sleep lead to atherosclerosis? In a diverse sample of over 1,600 individuals, we describe a pathway wherein sleep fragmentation raises inflammatory-related white blood cell counts (neutrophils and monocytes), thereby increasing atherosclerosis severity, even when other common risk factors have been accounted for. Improving sleep quality may thus represent one preventive strategy for lowering inflammatory status and thus atherosclerosis risk, reinforcing public health
more » ... public health policies focused on sleep health.
doi:10.1371/journal.pbio.3000726 pmid:32497046 fatcat:5d3oghfm6zd7llltgingzs5wli