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This paper uses a theoretical motivation for an Expanded Knowledge Production Function(EKPF) that encompasses both path dependence and spatial spillovers to search for evidences inBrazil using a Dynamic Spatial Panel Data approach. The purpose is to identify the determinantsof knowledge production in the 2005-2015 period as well as its temporal evolution, usinginnovation patents as proxies. Regarding its spatial distribution, we identified a North-Southdisparity for the knowledge production indoi:10.20396/rbi.v20i00.8661402 fatcat:ay6ztijkfvfh3jnoih6c7f7fr4