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Cellular Changes and Effect on DNA Integrity of the Epididymal Cells of Swiss Albino Mice Post Exposure to High Dose of Cyclophosphamide: A Histological and TUNEL Assay Study
International journal of science and healthcare research
Many studies done in past literature focuses on gonadal toxicity of Cyclophosphamide, but very less studies are done on the epididymis post exposure to this drug. Hence a sincere attempt is made in present study to look into the cellular changes in the epididymis through histology and TUNEL Assay. Subjects & Methods: Healthy male Swiss albino adult mice, were obtained from Central Animal Research Facility, Manipal were used for the study. The adult as well as prepubertal male mice were divideddoi:10.52403/ijshr.20220111 fatcat:nbovrp3bpfd7tnkkxuz4zj2rja