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Matrix topology guides collective cell migration in vivo
Diverse modes of cell migration shape organisms in health and disease and much research has focused on the role of intracellular and extracellular components in different cell migration phenomena. What is less explored, however, is how the arrangement of the underlying extracellular matrix that many cells move upon in vivo influences migration. Combining novel transgenic lines and image analysis pipelines, reveals that during zebrafish optic cup formation cells use cryptopodia-like protrusionsdoi:10.1101/2022.01.31.478442 fatcat:kzu3pufmdndc5jbhiq6sjrsdy4