Propositions 1. Sequence-based haplotyping in polyploid populations should make use of inheritance information. (this thesis) 2. The average read length influences the quality of sequence-based haplotyping more than sequencing depth. (this thesis) 3. The high expectations in genome editing are a result of a lack of knowledge about non-additive effects. 4. There is a positive correlation between the modesty of the first presentation of a new scientific concept and its long-term impact. 5.

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... ory inclusion of one PhD student in the thesis committee will bring more challenge and rigor to the PhD defense. 6. It is easier to find oriental food in the Netherlands than traditional Dutch cuisine. Propositions belonging to the thesis, entitled 'Haplotype estimation in polyploids using DNA sequence data'.