miRvar: A comprehensive database for genomic variations in microRNAs

Deeksha Bhartiya, Saurabh V. Laddha, Arijit Mukhopadhyay, Vinod Scaria
2011 Human Mutation  
microRNAs are a recently discovered and well studied class of small noncoding functional RNAs. The regulatory role of microRNAs (miRNAs) has been well studied in a wide variety of biological processes but there have been no systematic effort to understand and analyze the genetic variations in miRNA loci and study its functional consequences. We have comprehensively curated genetic variations in miRNA loci in the human genome and established a computational pipeline to assess potential
more » ... consequences of these variants along with methods for systematic curation and reporting of variations in these loci. The data is made available on the Leiden Open (source) Variation Database (LOVD) platform at http://genome.igib.res.in/mirlovd to provide ease of aggregation and analysis and is open for community curation efforts.
doi:10.1002/humu.21482 pmid:21618345 fatcat:tnfht5hac5hupmuiar7lh473t4