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AB023. S023. Identification and targeting of a poor-prognosis subgroup of pancreatic cancer
2018
Annals of Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) has the worst prognosis of all common cancers, but strongly divergent outcomes are apparent between patients. To reveal and address the intertumor heterogeneity that contributes to this, we have performed RNA-Seq gene expression analysis on a large number of resected PDAC samples (n=90). Unsupervised class discovery in this singlecenter PDAC-only dataset identified four subgroups with distinct clinical manifestations. Biological interpretation and network
doi:10.21037/apc.2018.ab023
fatcat:tjer5e345ff3fjsq5b6rza4rsi