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High genetic variation in the multidrug transporter cmeB gene in Campylobacter jejuni and Campylobacter coli
2006
Journal of Antimicrobial Chemotherapy
Objectives: This study was conducted to examine the genetic variation occurring in the cmeB gene encoding the transporter component of the CmeABC efflux pump. Methods: Expression of the CmeABC pump in 21 strains of Campylobacter jejuni and Campylobacter coli was studied by western-blot analysis. MIC determination was conducted in the presence or absence of an efflux pump inhibitor (EPI). Inactivation of the cmeB gene and sequencing of the cmeABC operon were performed for a single strain. The
doi:10.1093/jac/dkl212
pmid:16735430
fatcat:tzptld4n3vhcdedbessee3d4oe