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Sirolimus: a new promising immunosuppressive drug. Towards a rationale for its use in renal transplantation
2001
Nephrology, Dialysis and Transplantation
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Keywords: immunosuppressive drugs; rapamycin; renal IL4, in an autocrine or paracrine fashion. It also drives competent T-cell entry into the proliferation cycle via transplantation; sirolimus progression from the G1 to the S phase, with subsequent clonal expansion and the acquisition of T-cell effector functions.
doi:10.1093/ndt/16.1.18
pmid:11208987
fatcat:fjluswcuwve3hbhd3aacmyuh3u