Supplemental Figure 3: Microinjection of 4CIN into the VMH does not affect the counterregulatory hormone response. The specificity of the effects of the monocarboxylic acid transporter inhibitor, alpha-4-hydroxy cinnamic acid (4CIN), on the counterregulatory hormone responses was evaluated in a separate study comparing animals that received a microinjection (0.1ul/min for one minute) of either artificial extracellular fluid (aECF; Control; N=6)) or 4CIN (15nmol per side; N=7) immediately prior

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... o the induction of hypoglycemia. Peak plasma A) glucagon and B) epinephrine responses presented as a percentage of the average Control value, were similar between the two treatment groups. Data presented as mean ± SEM.