Modification of Source Strength in Low-Dose-Rate Lung Brachytherapy with 125 I and 103 Pd Seeds

Rezaei, Mostaghimi, Mehdizadeh, H Mostaghimi
2017 J Biomed Phys Eng   unpublished
Introduction L ung cancer has the highest rate of mortality among all cancers with more than 80% diagnosis of non-small-cell lung carcino-ma (NSCLC) [1, 2]. A new treatment approach for a wide range of high-risk patients with early-stage NSCLC who do not have proper respiratory conditions for lobectomy or pneumonectomy is wedge re-section plus low-dose-rate (LDR) permanent implant brachytherapy [3, 4, 5]. In this technique, a wedge-shaped piece of lung is removed by segmentectomy, and an
more » ... tomy, and an implant is created by weaving strands of LDR seeds (e.g. 125 I or 103 Pd) into a vicryl mesh which is then sutured over the resection staple line with the goal of delivering 100 to 120 Gy to the prescription point, 5 mm above the seeds plane [6, 7]. The implants are Original ABSTRACT Background: A new treatment approach for most patients who have undergone