Comparison of conjunctival autograft and intralesional Mitomycin C before bare sclera technique in pterygium surgery
IP International Journal of Ocular Oncology and Oculoplasty
Purpose: To compare the outcome and complications of conjunctival autograft and intralesional Mitomycin C (MMC) before bare sclera technique in pterygium surgery. Materials and Methods: This was a prospective cross sectional interventional study for 1 year after approval from the ethical committee. Patients of primary pterygium were randomly divided into two groups. Group I underwent pterygium excision with conjuntival autograft and group II underwent an intralesional injection of MMC (0.02% of
... on of MMC (0.02% of 0.05ml) in the head of pterygium one month before bare sclera surgery. Patients were followed up for minimum 6 months. Recurrence and complications in both the groups were noted. Results: Out of 60 patients, 43.3% were males and 56.6% were females with a mean age of 43.54 years. There was no significant difference in the preoperative and postoperative best corrected visual acuity and keratometry at 6 months follow up in both the groups and between the groups. Complications seen in our study were foreign body sensation in all patients , graft edema in 7 patients, subgraft haematoma in one patient in Group I and Foreign body sensation in one patient, Haematoma in one patient and suture granuloma in one patient in Group II. No case of sclera thinning or recurrence was seen. Conclusion: Recurrence can be safely reduced in bare sclera, with the use of MMC by this technique and can have comparable results with conjuntival autograft. Intralesional injection in the head of the pterygium can be safer as compared to direct exposure of MMC to the sclera.