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Upregulation of CD40 and CD40 Ligand (CD154) in Patients With Moderate Hypercholesterolemia
2001
Circulation
Background-Hypercholesterolemia, a risk factor for cardiovascular disease, is associated with inflammation and hypercoagulability. Both can be mediated by the CD40 system. This study investigated whether the CD40 system is upregulated in patients with moderate hypercholesterolemia and whether it is influenced by therapy with a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Methods and Results-Fifteen patients with moderate hypercholesterolemia and 15 healthy control subjects
doi:10.1161/hc4501.099312
pmid:11705814
fatcat:5x2gamayx5e7xbpbm63ltyojnq