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Nicardipine Prolonged-release Implants - A Potential Tool for the Prevention of Cerebral Vasospasm?
European Neurological Review
Despite considerable effort, no effective prophylactic treatment for cerebral vasospasm after subarachnoid haemorrhage (SAH) has been identified thus far. Treatment approaches have included the application of intravenous and therefore systemic vasodilatory drugs, which in turn have been found to be associated with significant side effects while at the same time exerting only limited efficacy. Consequently, a more local application, namely the intrathecal delivery of nicardipinedoi:10.17925/enr.2011.06.03.167 fatcat:xj6fjrovcbfvdjhdmgirjoge4y