Transition Metal Complexes of Sulfonamide Based Schiff Bases: Preparation Characterization and Antibacterial Activity

Ali Athar, A. Khan Khattak, W. Batool, F. Ullah, Z. Zia Ul Haq, M. Aman Ullah, J. Khuram, A. Fawad
2016
Metal complexes of Cu (II), Co (II), Ni (II) and Zn (II) of Schiff based derived from 2-hydroxy-7-methylquinoline-3-carbaldehyde and 2-hydroxy-7-methoxyquinoline-3-carbaldehyde with 3-aminobenzenesulfonamide have been prepared and characterized on the basis of their physical characteristics, micro-analytical data, 1H NMR, FTIR and UV spectrum data. The spectrum data confirmed coordination of Schiff base with metal through imine nitrogen and oxygen atom. While electronic spectrum data confirmed
more » ... rum data confirmed the octahedral geometry of the complexes. Biological screening effect of Schiff base and their metal complexes have been studied against gram positive and gram negative bacteria by disc diffusion technique. Biological activities show that the complexes exhibit higher antibacterial activity than that of Schiff base against tested bacteria.
doi:10.48317/morjchem.v4i4.5854 fatcat:yppeiinbrbhhtgsa3stbinjhmq