The relationship between C-reactive protein/albumin ratio and radiological findings in patients with COVID-19

Elif DEMİR, Ramazan GİDEN, Zeliha DEMİR GİDEN
2021 Journal of Contemporary Medicine  
Aim: Our aim in this study is to determine the C-reactive protein/ Albumin ratio (CAR) values of computed tomography (CT) -positive COVID-19 patients and CT-negative COVID-19 patients and to investigate the relationship between C-reactive protein/Albumin ratio and radiological images of patients. Material and Method: A-hundred COVID-19 patients over the age of 18 were included in our study. C-reactive protein (CRP), albumin levels and lung CT scan were collected. We divided the patients into
more » ... sections: CT-positive and CT-negative. We investigated the relationship between CT and CAR in patients, with and without comorbidity. Results: The measured CRP levels and CAR in the CT-positive group were significantly higher than CT-negative group (37.76±64, 9.05±22, p=0.001, 11.8±23.2, 2.12±5.42, p=0.0 01). The measured albumin levels of CT-positive group were significantly lower than the CT-negative group (4.12±0.63, 4.53±0.36, p=0.001). When we evaluate the patients by excluding those with comorbidity; CRP levels and CAR measured in the CT-positive group were significantly higher than in the CT-negative group. (15.94±19.2, 6.07±7.38, p=0.013, 4.57±6.82, 1.38±1.75, p=0.016). Although the albumin values of CT-positive patients were lower than those of CTnegative patients, no statistically significance was found. Conclusion: In general, we found that CAR levels in CT-positive patients were significantly higher than in CT-negative patients. In cases where CT is contraindicated (such as pregnancy), CAR can be used to indicate lung involvement or to follow-up patients with pulmonary involvement.
doi:10.16899/jcm.900886 fatcat:qmfrni6vwjg63li4wemmby3xfa