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Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming
2018
Nature Communications
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming" (2018). Open Access Articles. 3559. The transcription factor Nrf2 is a critical regulator of inflammatory responses. If and how Nrf2 also affects cytosolic nucleic acid sensing is currently unknown. Here we identify Nrf2 as an important negative regulator of STING and suggest a link between metabolic reprogramming and antiviral cytosolic DNA sensing in human cells. Here, Nrf2 activation
doi:10.1038/s41467-018-05861-7
pmid:30158636
fatcat:aagnu2s34ndudjn4liogmiocxu