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Investigating Causal Relationships between Inflammatory Bowel Disease and Autism Spectrum Disorder: A Bidirectional Two-sample Mendelian Randomization Study
[article]
2022
medRxiv
pre-print
and aims Inflammatory bowel disease (IBD) is usually comorbid with psychological disorders. Emerging observational studies have indicated the association between autism spectrum disorder (ASD) and IBD, including Crohn's disease (CD) and ulcerative colitis (UC), whereas the causality remains unknown. Our study aimed to explore the causal association between IBD and ASD using bidirectional two-sample Mendelian randomization (MR) design. Methods Summary-level data from large-scale genome-wide
doi:10.1101/2022.06.03.22275985
fatcat:zugzmtcstfdtrpyvt7wzuj4x2u