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Exploring bacterial outer membrane barrier to combat bad bugs
Infection and Drug Resistance
Ishan Ghai,1 Shashank Ghai2 1School of Engineering and Life Sciences, Jacobs University, Bremen, 2Leibniz University, Hannover, Germany Abstract: One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an effective change in the membrane permeability to antibiotics. The Gram-negative bacterial complex cell envelope comprises an outer membrane that delimits the periplasm from the exterior environment. The outer membrane contains numerous proteindoaj:094a07624139402ab89717a8897b29d8 fatcat:lh6tu6dmizdcjj3zrejw73cr5q