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Benchmarking UMI-based single cell RNA-sequencing preprocessing workflows
[article]
2021
bioRxiv
pre-print
Single-cell RNA sequencing (scRNA-seq) technologies and associated analysis methods have undergone rapid development in recent years. This includes methods for data preprocessing, which assign sequencing reads to genes to create count matrices for downstream analysis. Several packaged preprocessing workflows have been developed that aim to provide users with convenient tools for handling this process. How different preprocessing workflows compare to one another and influence downstream analysis
doi:10.1101/2021.06.17.448895
fatcat:5254sfwlbngifabgb5xpnbz4zu