A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is
The R Package MAMS for Designing Multi-Arm Multi-Stage Clinical Trials
Journal of Statistical Software
In the early stages of drug development there is often uncertainty about the most promising among a set of different treatments, different doses of the same treatment, or combinations of treatments. Multi-arm multi-stage (MAMS) clinical studies provide an efficient solution to determine which intervention is most promising. In this paper we discuss the R package MAMS that allows designing such studies within the group-sequential framework. The package implements MAMS studies with normal,doi:10.18637/jss.v088.i04 fatcat:hkzjdsez6fb5pdbjvgzpfazbsy