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Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells
2013
Stem Cell Research
Induced pluripotent stem cells (iPSCs) exhibit reduced efficiency and higher variability in neural differentiation compared to embryonic stem cells (ESCs). In this study, we showed that mouse iPSCs failed to efficiently give rise to neuronal cells using conventional methods previously established for driving mouse ESC differentiation. We reported a novel approach which remarkably increases neural differentiation of mouse iPSCs. This novel approach initiated embryoid body (EB) formation directly
doi:10.1016/j.scr.2013.01.003
pmid:23416351
fatcat:npay6p2ul5hntjb3ivztcr44hq