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Effect of dengue virus on procoagulant and fibrinolytic activities of monocytes
Reviews of Infectious Diseases
Some of the fibrinolytic and coagulation enzymes that monocytes produce are urokinase, a plasminogen activator (PA); a PA-specific inhibitor (PAI); and procoagulant activity (PCA), which has been characterized as tissue factor. Dengue infection in vivo is restricted to monocytes; however, it is unknown if dengue-infected monocytes undergo alterations in the production of PA, PAI, and PCA. This issue was addressed in studies in which monocytes were infected in vitro with dengue 2 virus inpmid:2501855 fatcat:w5gqbcr7mzb6xclqwdz6zu4otq