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Selective corticostriatal plasticity during acquisition of an auditory discrimination task
Perceptual decisions are based on the activity of sensory cortical neurons, but how organisms learn to transform this activity into appropriate actions remains unknown. Projections from the auditory cortex to the auditory striatum carry information that drives decisions in an auditory frequency discrimination task1. To assess the role of these projections in learning, we developed a Channelrhodopsin-2-based assay to selectively probe for synaptic plasticity associated with corticostriataldoi:10.1101/010066 fatcat:o4mtq545r5fsxkyyvzgmpvzlmq