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Advances in genomic medicine have the potential to change the way we treat human disease, but translating these advances into reality for improving healthcare outcomes depends essentially on our ability to discover disease- and/or drug-associated clinically actionable genetic mutations. Integration and manipulation of diverse genomic data and comprehensive electronic health records (EHRs) on a big data infrastructure can provide an efficient and effective way to identify clinically actionabledoi:10.1155/2016/3617572 pmid:27195526 pmcid:PMC4955563 fatcat:hlolgymxifelvlhpz2gneja36u