Optimization of chromatographic multi-component separations in silico using HTS-data

Anna Zofia Osberghaus
In this thesis critical issues concerning the application of mechanistic models for the development and optimization of chromatography processes are addressed and improved. A central topic of the thesis is the evaluation of chances and challenges for simulation and optimization when data from standard high-throughput experimentation (HTE) is included into model calibration.
doi:10.5445/ir/1000030554 fatcat:b3xtn64ucrayfd5m4xtqrie4fm