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Adult neurogenesis is tightly regulated through the interaction of neural stem/progenitor cells (NSCs) with their niche. Neurotransmitters, including GABA activation of GABA A receptor ion channels, are important niche signals. We show that adult mouse hippocampal NSCs and their progeny express metabotropic GABA B receptors. Pharmacological inhibition of GABA B receptors stimulated NSC proliferation and genetic deletion of GABA B1 receptor subunits increased NSC proliferation anddoi:10.1242/dev.102608 pmid:24284211 fatcat:6kiot2u2gjgpxj26igsnn34ywy