Chip multiprocessors (CMP) are widely used for high performance computing. Further, these CMPs are being configured in a hierarchical manner to compose a node in a cluster system. A major challenge to be addressed is efficient use of such cluster systems for large-scale scientific applications. In this paper, we quantify the performance gap resulting from using different number of processors per node; this information is used to provide a baseline for the amount of optimization needed when

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... all processors per node on CMP clusters. We conduct detailed performance analysis to identify how applications can be modified to efficiently utilize all processors per node on CMP clusters, especially focusing on two scientific applications: a 3D particle-in-cell, magnetic fusion application Gyrokinetic Toroidal Code (GTC) and a Lattice Boltzmann Method for simulating fluid dynamics (LBM). In terms of refinements, we use conventional techniques such as cache blocking, loop unrolling and loop fusion, and develop hybrid methods for optimizing MPI_Allreduce and MPI_Reduce. Using these optimizations, the application performance for utilizing all processors per node was improved by up to 18.97% for GTC and 15.77% for LBM on up to 2048 total processors on the CMP clusters.