The article presents studies of the Ursovit-ADES and sodium selenite effect on the biochemical and mor-phological parameters of the bull's blood in acute nitrate-nitrite toxicosis. The experiments were performed on bulls of six months of age, black-spotted breed. The combined use of chromosmone with Ursovit-ADES and so-dium selenite generally had a positive effect on the morphological and biochemical indicators of the blood under conditions of acute nitrate-nitrite toxicosis. It affected the

more »

... rovement of the functional state of the test animals and their rapid recovery. Furthermore, introducing the investigated drugs to animals helped reduce nitrates, nitrites, methemoglobin, ammonia, and leukocytes in the blood. Under these conditions, an increase in erythrocytes, hemoglobin, and urea was found. Therefore, the combined use of chromosmone, Ursovit-ADES, and sodium selenite in bulls to a greater extent has a curative and therapeutic effect, which helps to reduce the manifestations of endogenous intoxication.