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多次小剂量 STZ 诱导的成年鼠糖尿病指标的自发恢复 Diabetes induced by multiple low doses of STZ can be spontaneously recovered in adult mice
In a previous study, we observed that multiple low doses of streptozotocin (STZ) can induce spontaneous restoration of normoglycemia in adult mouse diabetes models. In the present study, we sought to identify when spontaneous recovery from diabetes occurs and to disclose the changes in the diabetic data of diabetic mice induced by multiple low doses of streptozotocin (MLD-STZ mice). After inducing type 1 diabetes mellitus, radioimmunoassay, indirect immunofluorescence and hematoxylin-eosinfatcat:yqxlw4ift5e4dngrns7nlrnkfu