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The prognostic significance of a histological response to preoperative chemotherapy in patients with synchronous colorectal liver metastases
Background Preoperative chemotherapy (PC) for colorectal liver metastasis (CRLM) is widely used to improve prognosis, but its clinical benefit has not been fully established. This study aimed to assess the effectiveness of PC for synchronous CRLMs, and to analyze the correlation between histological response to PC and survival. Methods We retrospectively analyzed the clinicopathological factors and outcomes of 69 patients who underwent initial hepatectomy for synchronous CRLM between 2004 anddoi:10.21203/rs.3.rs-280122/v1 fatcat:d7gbzkcwyfdlhklnomiewsqs54