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Objective: To evaluate fasudil effects on EAAT2 and ROCK2 protein expressions in rat model of neonatal hypoxic-ischemic brain damage (HIBD). Methodology: 144 Seven-day-old Wistar rats were randomly divided into sham, HIBD, and fasudil groups. Fasudil group were injected intraperitoneally with that compound. Rat brains at 2, 6,12, 24, 48 and 72 h after HIBD were collected to determine histopathological damage and the expression levels of EAAT2 and ROCK2 proteins selected as the average opticaldoi:10.21474/ijar01/3997 fatcat:vbugiwtcz5hwncibhimsggcsiu