Changes in the Balance between Caldesmon Regulated by p21-activated Kinases and the Arp2/3 Complex Govern Podosome Formation

Tsuyoshi Morita, Taira Mayanagi, Toshiyuki Yoshio, Kenji Sobue
2007 Journal of Biological Chemistry  
2 The abbreviations used are: RSV, Rous sarcoma virus; CaD, caldesmon; TM, tropomyosin; PAK, p21-activated kinase; N-WASP, neural Wiskott-Aldrich syndrome protein; Arp2/3, actin-related proteins 2/3; ECM, extracellular matrix; Rac1, Ras-related C3 botulinum toxin substrate 1; Cdc42, cell division cycle 42; siRNA, short interfering RNA; HA, hemagglutinin; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; CaM, calmodulin.
doi:10.1074/jbc.m609983200 pmid:17224451 fatcat:fmk2b4c7e5b3bip4bhz36jkxiq