Information on dissipation in the entrance channel of heavy-ion collisions is extracted by macroscopic reduction procedure of Time-Dependent Hartree-Fock theory. The method gives access to a fully microscopic description of the friction coefficient associated with transfer of energy from the relative motion towards intrinsic degrees of freedom. The reduced friction coefficient exhibits a universal behavior, i.e. almost independent of systems investigated, whose order of magnitude is comparable

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... ith the calculations based on linear response theory. Similarly to nucleus-nucleus potential, especially close to the Coulomb barrier, there are sizable dynamical effects on the magnitude and form factor of friction coefficient.