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The movement of a few large diameter spheres immersed in a granular medium composed of smaller beads in a rotating cylinder is studied. We evidence attractions and repulsions between the large spheres depending on the rotation frequency. The large spheres also show relative position fluctuations which are Gaussian. A complete study of this problem sheds new light on the problem of size segregation in granular materials and points to the importance of fluctuation-induced interactions.doi:10.1103/physrevlett.95.258002 pmid:16384511 fatcat:zysythxnkzbnvjyaag4tnpx3n4