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Immune suppression in gliomas
2020
Journal of Neuro-Oncology
The overall survival in patients with gliomas has not significantly increased in the modern era, despite advances such as immunotherapy. This is in part due to their notorious ability to suppress local and systemic immune responses, severely restricting treatment efficacy. We have reviewed the preclinical and clinical evidence for immunosuppression seen throughout the disease process in gliomas. This review aims to discuss the various ways that brain tumors, and gliomas in particular, co-opt
doi:10.1007/s11060-020-03483-y
pmid:32542437
pmcid:PMC7843555
fatcat:bqg2aeagl5cvnlubhecqo4msaq