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Leprosy (Hansen's disease) is a chronic infectious disease of mankind caused by Mycobacterium leprae. Despite several serious scientific attempts, M.leprae has never been cultivated in artificial bacteriological media. When M.leprae was identified as the causative germ of leprosy, Hansen (who discovered the causative germ of leprosy in 1873) attempted to cultivate the germ in animal models, but he failed. Nearly 85 years after the discovery of M. leprae successful transmission anddoi:10.23675/sjlas.v36i2.182 fatcat:j3knntysnzgclabielhecn4btu