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Clinicopathological and prognostic significance of PD-L1 expression in colorectal cancer: a systematic review and meta-analysis
2019
World Journal of Surgical Oncology
Objective: To analyze the prognostic value of programmed death factor ligand 1 (PD-L1) in colorectal cancer. Methods: Electronic databases, such as PubMed, Web of Science, Embase, and Cochrane library, were searched to identify studies evaluating the PD-L1 expression and overall survival (OS) in these patients. Afterwards, the relevant data were extracted to perform the meta-analysis. Results: A total of 3481 patients were included in 10 studies. The combined hazard ratio (HR) was 1.22 (95%CI =
doi:10.1186/s12957-018-1544-x
fatcat:2o4f4uh6hjdkne7v76wkbcq6eq