LONG-TERM OUTCOME OF CENTRALLY LOCATED LOW-GRADE GLIOMA IN CHILDREN

K. Terashima, K. Chow, J. Jones, C. Ahern, E. Jo, B. Ellezam, A. C. Paulino, M. F. Okcu, J. Su, A. Adesina, A. Mahajan, R. Dauser (+3 others)
2014 Neuro-Oncology  
BACKGROUND: Optimal management of children with centrally located low-grade glioma (LGG) is unclear. A better understanding of the inherent risk factors along with the effects of interventions on long-term outcome can lead to reassessment of the current approaches to minimize long-term morbidity. Our goal was to reassess the current treatment strategies to gain a better understanding of the benefits and risks of different treatment approaches. A secondary goal was to determine whether
more » ... e whether BRAF-KIAA1549 (B-K) fusion is associated with a better PFS. METHODS: To reassess the current treatment strategies of centrally located LGG, we compared the long-term survival and morbidity of different treatment regimens. Medical records of patients primarily treated at
doi:10.1093/neuonc/nou208.21 fatcat:4piw4gmmyjb7hbk25blwwmqh4u