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Blood Levels, Urinary Excretion and Serum Protein-Binding of 2- (2′-Methyl-3′-Chloro) Anilino Nicotinic Acid (SCH 10304) in Man
1971
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
Preserved Fulltext
Blood levels were determined after oral administration of SCH 10304 in man. Five healthy male volunteers received a single dose of 300 mg , two divided doses of 150 mg each, or a single dose of 150 mg. Male and female patients with rheumatoid arthritis received two divided doses of 150 mg each. The blood level reached a peak one or two hours after administration in subjects who received a single dose of 300 mg. The level was considerably lowered, but still detectable, six hours after
doi:10.3999/jscpt.2.340
fatcat:4aiawitykbdk3egfkkliwvj6fy