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Deletion of the voltage‐gated calcium channel, Ca V 1 .3, causes deficits in motor performance and associative learning
2022
Genes, Brain and Behavior
L-type voltage-gated calcium channels are important regulators of neuronal activity and are widely expressed throughout the brain. One of the major L-type voltagegated calcium channel isoforms in the brain is Ca V 1.3. Mice lacking Ca V 1.3 are reported to have impairments in fear conditioning and depressive-like behaviors, which have been linked to Ca V 1.3 function in the hippocampus and amygdala. Genetic variation in Ca V 1.3 has been linked to a variety of psychiatric disorders, including
doi:10.1111/gbb.12791
fatcat:2xpd6baqqffqnfbzmlcum7rp3i