Accuracy of triggers in the identification of adverse drug events in hospitalized elderly

Chriscia Jamilly Pinto de Sousa, Ana Cristina Lo Prete, Carolina Heitmann Mares Azevedo Ribeiro
2020 Research, Society and Development  
Objective: Evaluate trigger accuracy for identifying adverse drug events (ADEs) in hospitalised elderly. Methods: Two hundred patients 60 years old from a medical clinic within a private hospital were followed-up. For ADE identification the adapted Global Trigger Tool tracker methodology was used. Causality was determined using the Naranjo Algorithm. Results: Of the 200 elderly patients included in the study, 106 were females (53%), the average age was 79 years, and the average length of
more » ... ge length of hospital stay was approximately ± 10 days. Selected triggers were identified 1,457 times. The group of triggers with the best performance regarding its analysis accuracy was evolution triggers, with sensitivity of 69% and positive predictive value of 68%. In the individual performance analysis, the evolution tracker allergy, allergic reaction, pruritus achieved 100% performance for both sensitivity and positive predictive value. A total of 165 ADs were identified. Of these, 18% were phlebitis and 16% were hypoglycaemia. Drugs associated with ADE included insulin (15%) and Clarithromycin (9%). Conclusion: The triggering methodology has been effective for identifying ADEs. In addition, determination best trigger for constructing an ADE identification tool for hospitalised elderly was performed.
doi:10.33448/rsd-v9i12.11135 fatcat:wywi3ludevegxjtixdvylponsu