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Immediate in vivo response of the cortex and the blood–brain barrier following dynamic cortical deformation in the rat
1999
Neuroscience Letters
Although it is known that the brain can be injured by mechanical forces initiated at the moment of impact during trauma, it is not clear how the physical response of the brain dictates the injury patterns that occur in experimental models of traumatic brain injury. In this study, we investigated the mechanical response of the brain to a technique that creates a focal injury in the rat brain. Using a transient vacuum pulse applied to the exposed cortical surface, we found that the displacement
doi:10.1016/s0304-3940(98)00853-2
pmid:10027542
fatcat:temjwo3k5jgbtauptefbezs6di