This study sought to determine the impacts of quarry activities on the liver, kidney and hematological parameters of albino rats housed in the premises of the quarry site. Sixty male albino rats (Rattus novergius) aged 8 weeks and weighed between 115.5 to 128.6g were used in this study. They were housed in six wire cages with five 5 rats in each cage. Group 1 served as the control which was housed at a distance of 7.2km from the quarry site. Group 2 was housed at the crusher location of the

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... ry site while groups 3,4,5,6 were housed at the administration block, gate, plant house and drilling pit positions of the quarry site respectively. The results obtained reveal that the activities of serum alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and the concentrations of total protein, albumin and bilirubin differed in samples from different activity areas of the quarry site. Generally, levels of ALT, AST, ALP and bilirubin increased significantly (p<0.05) whereas the levels of total protein and albumin decreased significantly (p<0.05) when compared to the control. All the analyzed kidney function parameters were significantly higher (p<0.05) in the test samples than in the control samples. They were also significantly higher (p<0.05) in the dry season than in the wet season. Levels of hemoglobin (Hb), packed cell volume (PCV), red blood cell (RBC) and mean cell hemoglobin concentration (MCHC) were significantly lower (p<0.05) in the test samples than in the control sample in both seasons whereas, the levels of white blood cell (WBC), mean cell volume (MCV) and mean corpuscular hemoglobin (MCH) were significantly higher (p<0.05) in test samples than the control in both seasons. There was a clear and noticeable adverse effect of the quarry on the liver, kidney and hematological parameters of the albino rats. Therefore, workers in the quarry are at risks of anemia, kidney and liver diseases. Area of Study The quarry site lies within latitude 05 O 50 ' 18" N of the equator and longitude 07 O 25 ' 17" E of the Greenwich Meridian at Uturu Abia State Nigeria. Animal Sampling Sixty (60) male albino rats (Rattus novergius) aged 8 weeks and weighed between 115.5 to 128.6g were used in this study. They were housed in six (6) wire cages with five (5) rats in each cage. Group 1 served as the control which was housed at a distance of 7.2km from the quarry site. Group 2 was housed at the crusher location of the quarry site while groups 3,4,5,6 were housed at the administration block, gate, plant house and drilling pit positions of the quarry site respectively. All animals were allowed free access to feed and water ad libitum throughout the sampling period. The experimental animals were housed for ninety (90) days in each season (wet and dry seasons) and were sacrificed. The animals were anaesthetized in a desiccator containing cotton wool soaked in chloroform then sacrificed. Concentration Locations in the quarry site Urea (mg/dL) WET S. Urea (mg/dL) DRY S. Creatinine (mg/dL) WET S Creatinine (mg/dL) DRY S Bun (mg/dL) WET S Bun (mg/dL) DRY S