Steroid resistant Nephrotic syndrome (SRNS) is a therapeutic challenge for pediatricians and pediatric nephrologists worldwide. Currently, numerous immunosuppressive agents are used with variable efficacy. Results: Out of 44 SRNS children, Male: female ratio was 1.2:1. Nineteen (43.18%) children had Minimal Change Disease (MCD), 13 (29.54%) had Focal Segmental Glomerulosclerosis (FSGS), 7 (15.9%) cases had IgA Nephropathy (IgAN) and 3 cases had IgM Nephropathy (IgMN). Most (n=29; 65.9%) of the

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... hildren responded to Cyclosporin A (CyA). Thirty seven (84.1%) cases were late steroid responders. During follow up, 39 (88.64%) children were in complete remission. There were no major adverse effects except Cushingoid features and Hirsutism. Conclusions: In our study, MCD was most common histological subtype of SRNS and majority of the children responded to Cyclosporin A.