The title compound 3'-[(4-fluorophenyl)carbonyl]-5'-(hydroxymethyl)-4'-phenyl spiro[indole-3,2'-pyrrolidin]-2(1H)-one is synthesized by the straightforward multicomponent reaction of 1-(4-fluorophenyl)-3-phenylprop-2-en-1-one, isatin and serine, and is crystallises in monoclinic space group C2/c.The molecule is essentially planar except one of the pyrrolidin ring which adopts normal envelope conformation. The supermoleular assembly is consolidated by ᴨ-ᴨ interactions [centroid- centroid

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... = 3.7983(18)]. The crystal structure is stabilized by one C-H...O intra-hydrogen bond, two N-H...O and one O-H...N inter-hydrogen bonds, and these interactions links the molecules into chain extending along the b-axis.