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Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity
Journal of applied physiology
Zderic, Theodore W., and Marc T. Hamilton. Physical inactivity amplifies the sensitivity of skeletal muscle to the lipidinduced downregulation of lipoprotein lipase activity. Physical inactivity is a risk factor for lipoprotein disorders and the metabolic syndrome. Physical inactivity has a powerful effect on suppressing lipoprotein lipase (LPL) activity in skeletal muscle, the rate-limiting enzyme for hydrolysis of triglyceride (TG)-rich lipoproteins. We tested the ability of several compoundsdoi:10.1152/japplphysiol.00925.2005 pmid:16195388 fatcat:cg3mtcr44jecbljxjxplo27m6e