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The incidence of Invasive Fungal Disease (IFD) is increasing worldwide in the past 2 to 3 decades. Critically ill patients in Intensive Care Units (ICU) are more vulnerable to fungal infection. Early detection and treatment are important to decrease morbidity and mortality in critically ill patients. Objective: To profile critically ill patient associated with early invasive fungal disease. Method: Prospective cohort study was conducted on critically ill patients at Cipto Mangunkusumo Hospitalfatcat:ctjukclbmjeb7icbxuytsk26mu