A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
Effects of autophagy induction by low concentration of arsenate on survival and erythropoietin production in HepG2 cells
HepG2細胞における、低濃度ヒ酸によるオートファジー誘導が生存とエリスロポエチン産生に及ぼす影響
2020
HepG2細胞における、低濃度ヒ酸によるオートファジー誘導が生存とエリスロポエチン産生に及ぼす影響
Preserved Fulltext
We examined the effects of autophagy induction by low concentration of arsenate on cell survival and erythropoietin (EPO) production. Addition of 3-Methyladenine (3MA), an autophagy inhibitor, reduced both viability and EPO mRNA expression. Simultaneous addition of 3MA and arsenate increased autophagy and viability, but EPO mRNA expression remained low. These results suggested that autophagy induction by arsenate is more important for cell survival than EPO production, and that EPO production by arsenate is affected by autophagy.
doi:10.14869/toxpt.47.1.0_p-199
fatcat:tfqodebadbby3fqmkf2cvfuiq4